If I recall, didn't Gustavo pass away a couple years ago? Was it the kidney problems that took his life?
If I recall, didn't Gustavo pass away a couple years ago? Was it the kidney problems that took his life?
I thought I would share my pathology report with you all. Let my case be a warning to you to keep on top of your blood work and blood pressure measures. I am now left with 20% functioning kidney and will be discussing the procedures for a transplant in 2 weeks. I will keep you posted. All of this could have been avoided had I addressed symptoms years ago. KEEP HEALTHY!
Specimen
A Kidney biopsy, left - left native kidney
Clinical Information
The following information was submitted electronically by the ordering physician:
body builder, steroids, nephrosis and elevated creat
Gross Description
The specimen and patient identifiers are reviewed and are verified. The specimen consists of 2 cores of pale tan tissue. The larger core measures 1.3 cm. The shorter core measures 0.8 cm. The shorter core is divided (0.3 to EM) and (0.5 cm for IF). The larger core is submitted for light microscopy. ar/sg/sa 2014/11/05 10:00
Microscopic Description
Light Microscopy
Sections of kidney biopsy contain 9 glomeruli, 6 of which are globally sclerosed. The non-globally sclerosed glomeruli show focal segmental sclerosis. Otherwise, there is no significant increase in cellularity, no tuft necrosis, mesangial expansion and basement membrane changes. There is a background of mild tubular atrophy and interstitial fibrosis. There is no significant inflammation. The vessels are unremarkable. Histochemical staining with Congo red is negative for amyloid.
Immunofluorescence
Frozen tissue contains up to 9 glomeruli, 8 of which are globally sclerosed and one segmentally sclerosed. Immunofluorescence labeling is negative with IgA, IgG, IgM, kappa, lambda, fibrinogen and C3.
Electron Microscopy
3 globally sclerosed glomeruli are in the original tissue submitted for electron microscopy studies. Due to the lack of non-sclerosed glomeruli, the frozen tissue and paraffin embedded samples were reprocessed and made into toluidine blue stained sections. Toluidine blue stained sections examined contain 9 glomeruli, 8 of which are globally sclerosed and one segmentally sclerosed. Electron microscopy studies reveal diffuse sclerosis, with wrinkling of the basement membranes and hyaline deposition. There are dense areas, however, no definitive electron dense deposits or abnormal bodies are identified.
Diagnosis
Kidney (native, left), biopsy:
- advanced glomerulosclerosis, with focal segmental glomerular sclerosis (see comment).
Comment
The biopsy reveal severe glomerulosclerosis, with 17 of 21 glomeruli examined globally sclerosed. Of the non globally sclerosed glomeruli there is focal segmental sclerosis pattern. No electron dense or immunofluorescent deposits are identified.
Reviewed and electronically signed by:
ask you doc to send your urine for and ACR test (albumin to creatinine ratio test). 24hours are more accurate, but they are always messed up somehow - it's a very difficult protocol to follow accuratley
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