http://www.humankinetics.com/eJourna.../pdfs/5642.pdf (This is a really good article. Did you read through the whole thing?)
"Rapidly absorbed amino acids despite stimulating greater protein synthesis, also stimulate greater amino acid oxidation, and hence results in a lower net protein gain, than slowly absorbed protein (54). Leucine balance, a measurable endpoint for protein balance, is indicated in Figure 1, which shows slowly absorbed amino acids (~ 6 to 7 g/h), such as CAS and 2.3 g of WP repeatedly taken orally every 20 min (RPT-WP), provide significantly better protein balance than rapidly absorbed amino acids (39, 54)".
So I'm going to blow the whole meal frequency thing wide open right now. Conveniently I can do it with the article you posted 5151. So they used Leucine balance as a measure of protein balance. Leucine is the most abundant AA found in skeletal muscle so it makes sense. From what they wrote ideally a person would eat a 4:1 ratio of casein protien to whey protein every 20 minutes. Yielding what looks to be a maximum protein absorption rate of 5-8g/hr. They actually found that casein protein mixed with whey protein (4:1) is significantly more effective than ingesting amino acids or just whey protein. So if you eat a large meal with a lot of protein some of it ends up in your poop. Also, a lot of the protein you do absorb (since you don't need/can't utilize a large amount at any one time) ends up being converted to sugar via gluconeogenesis. This starts happening shortly after the amino acids enter the blood stream. Or, if protein is consumed with a large amount of carbohydrates. (like in a large infrequent meal). The amino acids are instead used to form triglycerides and you get fat storage).
So, for a bodybuilder. Eating frequently. Especially protein. Yields optimal Leucine balance, a decrease in conversion of amino acids to glucose or triglycerides. Also there is a thermic effect that is particularly associated with protein breakdown. This helps you stay lean. Eating meals frequently is just fueling the furnace, the evidence is everywhere.


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